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10 Best Supplements for Men

By Ethan Boldt

October 13, 2026

The perfect diet is loaded with nutrients, including fresh vegetables, fruits, properly sourced proteins, healthy fats and more. However, such a diet isn’t possible for most modern men, and as a result many men have nutrient shortfalls, such as vitamin D or magnesium.

While a diet that’s low in vitamin-rich foods like fruits and veggies is partly to blame, other factors like poor soil quality and lifestyle habits (aka too much stress) can also contribute to lower nutrient levels among men.

Normal aging is also to blame. For example, our levels of collagen, muscle mass and even bone density naturally decline as we age.

So for optimal health and healthy aging, it’s important to eat a balanced, healthy diet like the Mediterranean diet and get regular exercise … but also address any potential nutrient deficits with the right supplements, including ones that can aid performance and match your goals. (This can be especially true for active men.)

What kinds of goals? We’re talking improved muscle strength, lean muscle mass, fat loss, a faster metabolism, better sleep, improved heart and cognitive health, even better sexual performance.

So let’s examine the vitamins, minerals and supplements that can help you reach these goals.

(Note: You should always consult your healthcare professional before starting any dietary or lifestyle regimen, including dietary supplements.)

1. Multivitamin for overall health support

What vitamins are good to take daily? Overall, there are 13 essential vitamins all men need, plus a number of important trace minerals, electrolytes and essential fatty acids. The vitamins include C, A, D, E, K and the B vitamins (such as thiamine and vitamin B12).

A quality multivitamin includes most of these vitamins and minerals, and it can help address any potential nutrient shortages. Note that most multivitamins will usually cover one’s daily requirement for those shortfalls, with calcium and magnesium being two exceptions. (See more about those minerals below.)

Here are some of the critical vitamins and minerals for men and usually found in multivitamins in nearly 100 percent Daily Value (DV):

• Vitamin D: It's needed by men to produce enough testosterone, maintain strong bones, support brain health, support positive moods, and for healthy immune system and cardiovascular support. Yet 45 percent to 75 percent of all adults in the U.S. (or possibly even more depending on ethnicity) experience at least some degree of a vitamin D shortfall. It’s especially common among those who live in cold climates and spend most of their time indoors.

• B vitamins (B6, B12, folate, etc.): These are also needed by men for energy production, brain function and cardiovascular health. But as men age, the ability to absorb and use B vitamins may decrease … so it’s important to not just eat foods like beef, poultry and eggs but also potentially supplement.

• Antioxidant vitamins A, C and E: As men get older, these are also critical. They help promote antioxidant activity, support healthy cells, promote a healthy immune response, support cognitive health/healthy neuron function, and boost skin, eye and hair health.

• Vitamin K: Also important for men, it helps build and maintain strong bones, facilitate normal blood clotting and promote cardiovascular health. But a vitamin K shortfall can be common among men who don’t eat many vegetables or dairy products.

• Zinc: Found naturally in foods like organ meats, fish, legumes and nuts, zinc is an essential mineral for overall healthy immune system support and healthy metabolic function. It’s a component of more than 300 enzymes and participates in regulating enzymatic activity in the body every day.

• Potassium: Another key mineral, it helps maintain normal cardiovascular function, blood pressure, bone health and digestion. Nearly one in three adult men deal with low potassium levels, due to exercising more than an hour a day, excessive alcohol consumption, or certain over-the-counter or prescription medications.

Supplement suggestion: So you want to get a multivitamin with nearly 100 percent or more Daily Value of most of these vitamins and minerals. For example, Ancient Multi Men’s (formulated specifically for men under 40) and Ancient Multi Men's 40+ (formulated specifically for men in their 40s and beyond) provide 100 percent or or more Daily Value of 13 to 15 essential vitamins and minerals. To help support absorption and retention, take in divided doses — three capsules per day.

There’s also Men’s Once Daily options, in addition to Men's Fermented Multivitamin that is made with real food and fermented ingredients.

2. Creatine for strength, lean body mass and muscle recovery

Extensive research demonstrates that pairing creatine with resistance training significantly boosts muscle strength and enhances power output. Compared to training alone, adding creatine delivers greater overall benefits.

This advantage occurs because creatine accelerates the regeneration of ATP stores during high-intensity exercise, allowing you to maintain effort longer and reduce fatigue. The result is faster strength gains and better workout performance.

In addition, when paired with resistance training, creatine can significantly boost lean body mass over time, leading to better body composition — more muscle, less fat, and a more defined, sculpted look. This effect occurs because creatine supports energy production and brings water into the muscle, hence making creatine helpful for muscle growth.

Research also shows that creatine supports post-exercise muscle recovery and helps maximize the benefits of resistance training.

Lastly, research indicates that creatine provides support for overall brain health, including memory and learning, mental performance and attention, as well as motor function.

Supplement suggestion: The best creatine is creatine monohydrate, which is the most researched form. Look for high-quality, third-party-tested brands with no unnecessary fillers.

Ancient Nutrition’s Creatine + Collagen is one such brand and supplement. It’s the only creatine on the market that combines creatine with a specific collagen ingredient. This formula combines 5g of creatine monohydrate and clinically validated fermented eggshell membrane collagen to build lean body mass, recovery and cognitive health. The fermented eggshell membrane collagen also helps improve joint comfort, mobility and recovery.

3. Whey protein for lean muscle mass support

Whey protein has been a consistent go-to supplement for men when it comes to muscle building. With a high percentage of branched-chain amino acids, whey promotes the maintenance of muscle tissue and helps to guard against muscle breakdown during exercise.

Whey protein benefits also align very well with muscle gain goals. Numerous studies indicate that whey protein can promote gains in lean muscle mass, especially when paired with strength training. Whey also stimulates more muscle synthesis than casein or soy protein products.

It is also sometimes considered a top protein powder for healthy weight management because it can help curb cravings and improve body composition.

Supplement suggestion: Ancient Nutrition’s Whey Protein (available in vanilla bean, milk chocolate and chocolate peanut butter flavors) contains 23 grams of protein per scoop. It’s made with grass-fed, organic and regenerative A2/A2 milk protein. This is whey that comes from cows that produce only the A2 type of beta-casein, which is similar to the primary protein found in human milk and is often easier for humans to digest.

Benefits of Ancient Nutrition’s whey protein include building strength, increasing lean muscle mass, supporting healthy body composition and promoting satiety.

Another element that sets this whey protein apart from others? It includes clinically studied eggshell membrane collagen, so this Whey Protein can also help promote joint health and improve mobility (with the added benefits of improving skin appearance and hair health).

4. Omega-3s for heart health support

Most men eating a “Western diet” consume plenty of omega-6 fatty acids, which are pro-inflammatory and found in many ultra-processed foods (packaged foods and vegetable oils, for example). Meanwhile, not enough omega-3 fatty acids — which support healthy inflammation levels and are found in certain fish, eggs, nuts and seeds — are consumed.

Ideally, all men should consume a ratio of omega-6s to omega-3s that’s between about 2:1 to 4:1 (so roughly double the amount of omega-6s than 3s). However, some men might be consuming up to 10 times more omega-6s than this.

The two need to balance each other out in order to help keep inflammation levels at a healthy, normal level and promote healthy heart, brain and immune system functions.

Supplement suggestion: Eating wild-caught fish several times per week, or taking an omega-3 fish oil supplement equal to about 1,000 milligrams daily, is the best way to ensure you get enough.

Ancient Nutrition’s Omega-3s Whole Body soft gels contain 1,100 milligrams of omega 3s, plus omega 6s and 9s — all from both wild ocean and plant-based sources.

5. Collagen for healthy aging and joint health support

Collagen is the most abundant protein in the human body. This “structural protein” helps to build and support healthy connective tissues throughout the body — the joints, ligaments, tendons, skin, bones, blood vessels and even the lining of the gastrointestinal tract and other organs.

As a complex protein, collagen is made up of smaller “building blocks'' called amino acids. It generally contains 19 amino acids and is an especially ample source of several that aren’t abundant in many other protein sources such as meat or fish — including glycine, proline and arginine.

Benefits of collagen for men generally include helping to support joint comfort and mobility, overall maintenance of muscle mass, exercise performance and recovery, as well as skin health. Collagen also promotes hair health and hair growth.

Supplement suggestion: Ancient Nutrition’s Multi Collagen Protein supplements feature 10 types of collagen from four food-sources: chicken, bovine, fish and eggshell membrane. The hydrolyzed collagen supports absorption due to the positive effects of collagen fermentation. These formulas are sourced from only grass-fed and pasture-raised, cage-free and cruelty-free sources, and have no added sugar, additives and fillers.

Multi Collagen Protein’s proven benefits are rapid and real for men. They include:

• Reduces joint discomfort and helps joints recover faster

• Reduces knee stiffness at 7 days

• Promotes healthy hair thickness and growth with a reduction in hair breakage

• Improves the appearance of crow’s feet after 4 weeks

A general serving amount of collagen for men is one or two servings per day, or about 10 to 20 grams of collagen and 9 to 18 grams of protein daily. Some men may want to work up to possibly taking three daily servings, depending on their overall diet and goals as well as the input of their healthcare professional.

Ancient Nutrition also offers a Multi Collagen Advanced premium supplement line. It features products aimed to help one lose weight and fat, gain muscle and strength, rapidly hydrate, promote healthy detoxification and support longevity. Each Multi Collagen Advanced formula is packed with 10 types of collagen from 10 food-based sources, including six premium grass-fed organs as well as a unique, clinically studied blend of superfood ingredients.

For example, Multi Collagen Advanced Muscle Capsules uses select ingredients to boost lean body mass. This supplement features a proprietary muscle building blend that includes East Indian globe thistle and mango bark extract.

Ancient Nutrition's Bone Broth Protein (which also contains collagen) also supports joint health, gut lining and lean muscle recovery.

6. Supplements for men's health concerns (prostate, libido and testosterone)

While men share many health concerns with women such as joint, skin and heart health, there are some concerns that mostly involve men — in particular, testosterone, libido and, exclusively, prostate health.

As men age, natural changes in hormone levels, prostate size and circulation can influence these important aspects of men's health. The prostate commonly enlarges over time, potentially affecting urinary comfort and function. Testosterone levels may gradually decline, influencing muscle mass, bone strength, energy and sexual desire.

Meanwhile, changes in hormones, cardiovascular health, stress and other lifestyle factors can affect libido and sexual performance. Although these changes are common, they aren't inevitable for every man. Maintaining a healthy lifestyle and addressing emerging symptoms can help support men's health and quality of life well into later adulthood.

Supplement suggestion: Ancient Nutrition created three targeted supplements for these male concerns.

Men’s Testosterone Booster is a daily, multi-benefit formula designed for men who want to feel energized, driven and confident while navigating the demands of work, fitness and healthy aging. By combining efficacious amounts of clinically studied ingredients with a targeted blend of vitamins and minerals, this comprehensive formula supports male vitality, energy, performance and healthy testosterone levels.

Men’s Prostate Support is a once-daily targeted daily formula designed to support prostate and urinary wellness as men age. By intentionally combining certain clinically studied ingredients, this comprehensive formula supports healthy prostate function, urinary flow and frequency during the day and overnight.

Men’s Libido Booster is a daily, comprehensive formula designed to support the interconnected factors behind male sexual wellness. By intentionally combining clinically studied ingredients and a seven-plant botanical blend, this stimulant-free formula offers comprehensive support from desire to performance.

7. Probiotic for gut health support

Gut health is especially important for men because it plays a role in digestion, nutrient absorption, immune function, metabolism and overall well-being. As men age, changes in diet, lifestyle and the gut microbiome can contribute to digestive discomfort, irregularity and metabolic health concerns.

Emerging research also suggests connections between the gut microbiome and hormonal balance, cardiovascular health and the gut-brain axis. Supporting a healthy gut through fiber-rich foods, fermented foods, regular exercise and other healthy habits can help men maintain digestive function and support long-term wellness.

Supplement suggestion: The best probiotic formulations for men can help to maintain a healthy balance of gut flora, help support nutrient absorption, and even play a role in supporting healthy immune system function.

Ancient Nutrition’s SBO Probiotic Men’s is formulated specifically to support men’s health, not only by providing healthy microbes for digestive health support but also other beneficial botanicals and herbs tailored for men’s health. It’s made to support digestive and immune system health. It features a combination of soil-based organisms (species of probiotic bacteria that are often hardier than other types of probiotics) and an organic fermented botanical blend of fenugreek, ginger, fo-ti root and an organic mushroom blend of turkey tail, shiitake, reishi and maitake.

There's also a SBO Probiotics Men's Once Daily supplement as well.

8. Magnesium for supporting healthy blood pressure levels support

Magnesium is an essential electrolyte mineral involved in over 300 different biochemical reactions in the body. It plays a part in regulating calcium, potassium and sodium levels, thereby supporting healthy blood pressure, muscular health, digestive processes, bone health, a positive outlook and calmness, and many other processes.

However, levels of magnesium in the modern food supply are believed to have decreased over time due to soil depletion, which is one reason why men might be getting less. Dealing with stress and working out often can also diminish one’s magnesium levels.

Supplement suggestion: Besides consuming magnesium-rich foods — such as leafy green veggies, cruciferous veggies, beans, nuts and seeds — some men should consider supplementing with extra magnesium. The average multivitamin doesn’t contain much magnesium, while most healthy adult men should generally consume about 400 to 420 milligrams of magnesium daily.

Ancient Nutrients Magnesium contains 300 milligrams of body friendly magnesium. Meanwhile, Ancient Nutrition’s Active Peptides Magnesium Complex combines four highly bioavailable forms of magnesium, clinically validated ashwagandha and other supporting nutrients designed to help with stress, sleep, mood and energy.

9. Electrolyte powder for hydration support

Cardio exercise, especially in warmer weather, can cause plenty of normal body fluid loss through both sweat and electrolyte dilution. Even low-intensity exercise can lead to the need to rehydrate to promote proper fluid replacement.

Electrolyte drinks help replenish some of the sodium, potassium, magnesium and calcium lost so you can achieve peak performance and stay hydrated. Plus, it can assist in overall hydration, as many men simply don't drink enough fluids.

Supplement suggestion: To help you achieve rapid hydration for both skin and body, consider Ancient Nutrition's Multi Collagen Advanced Hydrate Powder (lemon lime or mixed berry flavor) supplement It provides twice the number of electrolytes (overall sodium and potassium levels) compared to leading sports drinks, and it features a sugar-free hydration superfood blend.

Meanwhile, Ancient Nutrition's Rapid Hydration powder — available in stick packs — delivers essential electrolytes for fast-acting hydration, all powered by real food ingredients: coconut water, natural sea salts and red marine algae. It, too, is made without sugar.

10. Calcium (if over age 50) for bone health

As men age, maintaining adequate calcium intake becomes increasingly important for supporting bone density, muscle function and overall skeletal health. Although osteoporosis is more common in women, men also experience age-related bone loss, particularly as testosterone levels decline.

Men ages 51–70 need approximately 1,000 milligrams of calcium daily, while those 71 and older need 1,200 milligrams. A calcium supplement may help men who aren't getting enough through their diets, but supplementation isn't necessary for everyone. Note that multivitamins don't contain much calcium.

If you do choose a calcium supplement, ideally it’s coupled with vitamin D, which supports calcium absorption.

Supplement suggestion: Along with calcium-rich foods like dairy products, leafy greens, beans and sardines, consider a supplement like Ancient Nutrients Calcium, which provides 574 milligrams of food-form calcium. A non-dairy calcium source, it supports bone health. It also features vitamin D3, which, in general, acts as a supporting role in the body’s absorption of calcium. (Calcium does not appear in a significant amount in any multivitamin.)

Bonus: an organ supplement

Some experts, and many practitioners of traditional health systems, believe that organ meats — including beef liver — are among the most, if not the most, nutrient-filled superfoods on the planet. This is especially true when the organs/glandulars are sourced from healthy, properly raised animals, which tend to hold more nutrients in their bodies.

Ancient Nutrition's Male Performance is a wild, grass-fed organ blend packed with male-specific nutrients to help you feel energized. It supports men's health, including healthy male performance, youthfulness and vigor. It also supports healthy hormones and immune system health. There's also Once Daily Male Performance tablets.