SBO Probiotics Men's Capsules (60 Capsules)
Quantity: 1-Pack ($49.95 per unit)
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Suggested Usage
Product Facts
Dietary Restrictions
  • Features 25 billion CFUs*
  • Four probiotic strains: Saccharomyces boulardii, Bacillus coagulans, Bacillus clausii and Bacillus subtilis
  • Supports healthy digestive function†
  • Reduces occasional constipation, gas and bloating†
  • Supports a healthy immune system†
  • Promotes healthy bowel function and supports healthy elimination†
  • Helps to maintain healthy gut microflora†
  • New and improved formulation for more targeted support
Adults take two capsules daily with 8 ounces of water
We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed
Not intended for children
Form: Capsule
Serving Size: 2 Capsules
# of Servings: 30
Product Weight: 1.7 ounces


Designed specifically for the male body, this formula combines time-tested mushrooms and fermented botanicals - like organic ginger root, fenugreek and fo-ti root - with a tough, clinically studied strain of soil-based probiotics. Each daily serving brings you 25 billion CFUs (at time of manufacture). We’ve also added crucial pre- and postbiotics, which serve as fuel for probiotics and help the good bacteria thrive. Created exclusively for men, this formula is designed to help your gut work smarter - not harder.



Saccharomyces boulardii

This beneficial, tropical species of yeast ingredient in SBO Probiotics functions as a probiotic to help support overall gut health and function. It’s one of the few yeasts that survives best at the human body temperature, giving it the capacity to stay in the game and plays its role in digestive health.


Bacillus subtilis

A soil-based probiotic that supports healthy gut flora, healthy bowel function, healthy digestive function a healthy immune system, in addition to reducing occasional gas and bloating.† Bacillus subtilis (B. subtilis) — also known as hay bacillus or grass bacillus — generally has an extraordinary ability to survive harsh conditions of heat, dryness, humidity and acidity in the environment. For men, who typically produce more stomach acid than women, this could be a game changer.


Bacillus coagulans

This shelf-stable strain supports healthy bowel transit time, digestive function, oral health and healthy gut flora.†


Bacillus clausii

Bacillus clausii is a hardy probiotic that has the unique ability to withstand high pH environments. It’s a tough strain that performs in conditions that many other probiotics can’t.

Full List of Ingredients

Zinc, Selenium

SBO Men Probiotic Blend
Saccharomyces boulardii, Bacillus coagulans, Bacillus clausii, Bacillus subtilis

Organic Fermented Botanical Blend
Organic Fermented Ginger Root, Organic Fermented Fenugreek Seed, Organic Fermented Fo-Ti Root

Organic Mushroom Blend
Organic Turkey Tail (trametes versicolor) Mycelium, Organic Shiitake Mycelium, Organic Reishi Mycelium, Organic Maitake (Grifola frondosa) Mycelium

Other ingredients: Hypromellose

Nutrition Information

Serving Size:

2 Capsules

Servings Per Container:


Amount Per Serving: % Daily Value
Zinc (from zinc amino acid chelate) 15mg 136%
Selenium 100mcg 182%
SBO Men Probiotic Blend 634mg (25 Billion CFU*)
Organic Fermented Botanical Blend 480mg
Organic Mushroom Blend 75mg

% Daily Values are based on a 2,000 calorie diet.

* Daily Value not established.


Designed for Men

We took this formulation a step further by adding a blend of ingredients generally known to support men's overall health. We consider this the best probiotic for men. Specifically, these probiotics work to support men's healthy digestive system, immune system health† and more.


Many probiotic strains are fragile and require refrigeration to survive. Even when you take them, they may not all make it into your gut to colonize. SBOs are resistant to extremes in temperature as well as the harsh environment of the digestive tract. These strains are tough and survive without refrigeration.

Trifecta Effect

SBO Probiotics offer a trifecta approach in its formulation for prebiotic, probiotic and postbiotic support setting the stage for, with and following the SBO Probiotics. Probiotics are the good bacteria in our bodies. Prebiotics are typically non-digestible fiber compounds that help probiotics thrive. This formula also brings in ancient ingredients, like an organic mushroom blend and an organic fermented botanical blend, which can help foster prebiotics and set the stage for the soil-based organisms.

Diverse Probiotic and Yeast Strains

This probiotic blend features four diverse strains to support the gut in multiple ways, including maintaining healthy gut microflora, support for healthy digestive function and a healthy immune system.†

SBO Probiotics support healthy gut function, which has an impact on nutrient absorption, your energy levels and overall outlook. Incorporating these soil-based organisms and probiotics into self-care routine may support healthy energy levels and overall well-being.
Dr. Josh Axe

How to Use

Day-to-Day Usage

Day-to-Day Usage

Take two capsules per day with water or your favorite beverage. Can be taken with or without food. These are great first thing in the morning on an empty stomach or before bed. Because they don't require refrigeration, try keeping them beside your bed for more convenience.

Maximize Experience

Maximize Experience

Make the most of SBO Probiotics Men’s by eating a gut-supporting diet featuring prebiotics and fermented foods such as kimchi, kombucha or sauerkraut while managing emotional stress and limiting exposure to environmental toxins that disrupt the gut microflora.

Pairs Well With

Pairs Well With

If you're looking for additional support, try Ancient Nutrition – Men’s Fermented Multi, which offers multivitamin and mineral support in a real food, fermented form.

Ancient Nutrition – Men’s Fermented Multi

Frequently Asked Questions

Frequently Asked Questions

Dr. Axe Answers

Ancient Nutrition co-founder, chiropractor, clinical nutritionist and certified doctor of natural medicine is here to answer your questions!

What does Bacillus subtilis do?

In general, Bacillus subtilis can manage the harsh stomach acid environment, allowing it to get to the digestive system and colonize its beneficial bacteria. Bacillus subtilis is truly a hardy, tough probiotic that is resilient and highly adaptable.

Do I need to refrigerate these probiotics?

Our SBOs arrive dormant and are stable at room temperature, without refrigeration.

Why should I give my gut extra support?

Fact: Most Americans don’t consume enough probiotics in their diet due to modern processed foods, soil depletion and more. I believe most people are in need of probiotic support.

Here’s why: Thanks to prescription antibiotics, high carbohydrate diets, fluoridated tap water and high levels of stress, the good bacteria in our guts are often diminished, and our bodies can't replace them at the rate required for optimal health.

Many of probiotics’ health benefits are gut- and digestion-related, so here are a few key reasons why gut health, in general, is so important to overall health:

  • Up to 80% of the immune system is housed in the gut.
  • Between 80% to 90% percent of the body’s serotonin, often referred to as a “feel good” or “happy chemical” which acts as a neurotransmitter, is found in the gut. Serotonin is thought to have many effects on the body, including the areas of digestion, sleep, memory, behavior and more.
  • Every bodily cell, tissue and organ depend on proper nutrient absorption and assimilation of food through healthy digestion, and, generally speaking, probiotics can play a supporting role in that.

What is the right amount of CFUs to be getting every day?

It varies. For most people, I recommend a CFU count anywhere between 25 to 100 billion. This probiotic formula features 25 billion CFU* per serving. *at time of manufacture

What's the best time to take probiotics?

To help support absorption and colonization in the gut, we recommend taking probiotic capsules on an empty stomach, either when you first wake up or right before bed (roughly 2–3 hours after your last meal).

Generally, what makes soil-based probiotics different from other types of bacteria and yeasts?

Soil-based organisms are often stronger than other forms of bacteria since they don't require refrigeration (meaning they're shelf-stable) or any special handling. They can generally survive the journey through the stomach to the intestines.

Soil-based organisms are typically able to seed the digestive tract with beneficial bacteria which can grow and flourish, supporting overall healthy digestion and a healthy immune system. †

How is this product different from the probiotics in your Ancient Probiotics line?

The main difference is that this SBO Probiotics formula features primarily soil-based, spore-forming organisms, and Ancient Probiotics features mostly non-spore forming cultures.

The strains in SBO populate differently in your gut than the live cultures in Ancient Probiotics, so they are great to take together for more strain diversity.

SBO Probiotics feature a fermented botanical blend of prebiotics, while Ancient Probiotics do not. Ancient Probiotics feature Ayurvedic herbs; SBO Probiotics does not feature these.

Ancient Probiotics varieties feature anywhere between 25 billion and 100 billion CFU* per serving, and SBO Probiotic- Men's features 25 billion CFU* per serving.

Soil-based organisms are generally more survivable than live cultures, which is why there are 16-17 strains of probiotics in Ancient Probiotics and three strains in SBO Probiotics and one beneficial yeast. *at time of manufacture

Is this dairy-free?

These probiotics are made without dairy - we removed the Lactobacilli strains found in our classic SBO Probiotic formulation.

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